ncRNA name | hsa-miR-376a |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell line HXO-RB44 |
Methods | flow cytometry, microarray, qRT-PCR, transfection, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | ATO -induced apoptosis in retinoblastoma cells is part mediated by decreasing expression of miR-376a, which subsequently increased caspase-3 expression. |
PubMed ID | 23373993 |
Year | 2013 |
Title | Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.